"Anti-Coronavirus Marine Bioactive Compounds

This unique volume summarizes emerging approaches based on in silico in vitro in vivo and clinical studies to uncover the potential and the underlying mechanisms of diverse marine bioactive compounds to inhibit SARS-Co V-2 and its variants and hence pave the way for drug discovery devoted to the management of COVID-19. Investigating a range of natural compounds for their anti-SARS-Co V-2 activity this volume offers in-depth insights into molecular mechanisms that can inhibit viral/host protein targets of SARS-Co V-2. It highlights the action of marine bioactive compounds based on advanced bioinformatics tools such as molecular docking computer simulation and systems pharmacology as well as multiple omics and high-throughput technologies. Chapters discuss the modes of action by selected marine polysaccharides terpenoids astaxanthin and an indole-alkaloid (holyrine A) for combating SARS-Co V-2 and propose their potential role in COVID-19 management. Finally a chapter discusses the role of marine bioactive compounds that include some traditional remedies from Southeast Asia for combating SARS-Co V-2 infection. Providing valuable knowledge based on state-of-the-art literature that highlights the anti-SARS-Co V-2 activity of marine bioactive compounds this work will be an important resource for researchers professors and experts in diverse sub-fields of life sciences such as virology pharmaceutical science and drug discovery medical research biochemistry bioinformatics biomedical science computational biology epidemiology and other areas. The book presents approaches that are potentially useful for the management of global public health and can support the goal of establishing Good Health and Well-Being which is one of the Sustainable Development Goals (SDGs) 2030 of the United Nations. |Anti-Coronavirus Marine Bioactive Compounds