Charnolophagy In Health And Disease With Special Reference To Nanotheranostics | Science Publishers

This book introduces charnolophagy (CP) as energy-driven lysosomal-dependent mitochondrial inclusion-specific pleomorphic Charnoly body (CB) autophagy (ATG) involving free radical-induced Ca2+ dyshomeostasis ΔΨ collapse and ATP depletion in congenital diseases pressure ulcers metabolic diseases hepatic diseases diabetes obesity inflammatory diseases musculoskeletal diseases sarcopenia cachexia respiratory diseases gastrointestinal diseases hyperlipidemia skin and hair diseases pulmonary diseases cardiovascular diseases renal diseases sepsis-induced multi-organ failure reproductive diseases inflammatory diseases ophthalmic diseases neurodegenerative diseases drug addiction aging microbial (including COVID-19) infections and belligerent malignancies implicated in early morbidity and mortality and disease-specific spatiotemporal targeted safe and effective evidence-based personalized theranostic charnolopharmacotherapeutics to cure them. Basic DRESS and GELS principles nanoparticles to cure chronic multidrug-resistant (MDR) diseases antioxidants as free radical scavengers CB antagonists CP regulators and CS stabilizers to curb CB molecular pathogenesis (CBMP) are described for better quality of life and longevity. Specific guidelines for environmental protection and preservation of zoological and botanical species at the verge of extinction Triple I Hypothesis for mitochondrial quality control and transcriptional regulation of CSex R and CSendo R to cure chronic diseases are presented. Novel CP index is introduced to evaluate MDR malignancies and other chronic diseases. WHO CDC FDA NIH policy planners cosmetologists trichologists players athletes dancers wrestlers equestrians young women aging population toxicologists environmental protectionists pharmaceutical industry biomedical scientists researchers medical students physicians nurses paramedical professionals and global audience will be interested in this interesting book to prevent pandemics and raise healthcare awareness. |Charnolophagy in Health and Disease With Special Reference to Nanotheranostics | Science Publishers