Retinol Serum for Skin Renewal | Does your skin feel dull, tired, and lifeless? Discover the magic of retinol in this anti-wrinkle serum. Endocare Renewal Retinol 0.5%. Smoothes skin, softens fine lines, and evens out skin texture. RetinSphere® technology provides effective skin renewal and improved firmness. Wake up every morning with una visibly more radiant and rejuvenated skin.