This book constitutes the refereed proceedings of the 22nd International Conference on Practical Applications of Agents and Multi-Agent Systems, PAAMS 2024, held in Salamanca, Spain, during June 26-28, 2024. The 26 full papers and 6 short papers included in this book were carefully reviewed and selected from 64 submissions. The PAAMS 2024 proceedings focus on the development and deployment of agents and multi-agent systems and their real-world applications.
