Why do we get certain diseases whereas other diseases do not exist? In this book Alon one of the founders of systems biology builds a foundation for systems medicine. Starting from basic laws the book derives why physiological circuits are built the way they are. The circuits have fragilities that explain specific diseases and offer new strategies to treat them. By the end the reader will be able to use simple and powerful mathematical models to describe physiological circuits. The book explores in three parts hormone circuits immune circuits and aging and age-related disease. It culminates in a periodic table of diseases. Alon writes in a style accessible to a broad range of readers - undergraduates graduates or researchers from computational or biological backgrounds. The level of math is friendly and the math can even be bypassed altogether. For instructors and readers who want to go deeper the book includes dozens of exercises that have been rigorously tested in the classroom |Systems Medicine Physiological Circuits and the Dynamics of Disease | Computer Science
