This book constitutes the proceedings of the First Interdisciplinary Workshop on Reponsible AI for Value Creation, REPAI-W 2025, which took place in Copenhagen, Denmark, during December 1, 2025. The 6 full papers included in thie proceedings were carefully reviewed and selected from 9 submissions. The book also contains one invited paper. They deal with AI solutions over complementary disciplinesâsuch as technical AI development, ethics, law, organizational studies, and value creationâto deepen the understanding of AIâs role in real-world practice and shape its responsible use.