Amino Acids: Insights And Roles In Heterocyclic Chemistry Volume 2: Hydantoins T

This is the second volume of a first-of-its-kind four-volume book set that provides readers with up-to-date information on α-amino acids the potential challenges in working with α-amino acids the protecting groups for the carboxyl amino and side chain groups of the amino acids and the most popular heterocyclic compounds that are originating from alpha-amino acids. These heterocyclic compounds include hydantoins thiohydantoins (including 2-thiohydantoins 4-thiohydantoins 2 4-dithiohydantoins) 2 5-diketopiperazines N-carboxyanhydrides N-thiocarboxyanhydrides sydnones sydnonimines azlactones pseudoazlactones and oxazolidin-5-ones. This is the first resource to comprehensively collect all the heterocycles that can be directly prepared from α-amino acids. In addition almost all kinds of synthetic methods for a particular type of heterocycles from alpha-amino acids are included along with the detailed mechanistic discussions and experimental procedures. In Volume 2: Hydantoins Thiohydantoins and 2 5-Diketopiperazines compiles the three IUPAC accepted nomenclature systems for heterocyclic compounds which will be very useful for readers working in the heterocyclic chemistry field for giving synthesized molecules their correct names. In addition three groups of heterocyclic compounds i.e. hydantoins thiohydantoins (including 2-thiohydantoin 4-thiohydantoin and 2 4-dithiohydantoin) and 2 5-diketopiperazines have been organized with updated literature information. Particularly all three groups of heterocyclic compounds have demonstrated many important biological activities particularly anticancer and antibacterial activities. On the other hand these three groups of heterocycles can be applied as substrates to make other chemical derivatives particularly novel unnatural amino acids. All their reactivities have been compiled and updated. The other volumes include: Volume 1: Protecting Groups Volume 3: N-Carboxyanhydrides N-Thiocarboxyanhydrides and Sydnones Volume 4: Azlactones and Oxazolidin-5-ones All together this unique 4-volume set thoroughly covers the two types of heterocyclic compounds that are originated from alpha-amino acids providing carefully compiled updated information with detailed examples. The author has shared many thoughtful insights based on his strong background in physical organic chemistry. The volumes will be highly valuable for graduate students and senior students as well as for professors and researchers working in the field of medicinal and pharmaceutical chemistry organic chemistry organic synthesis heterocycles and proteins and peptides. |Amino Acids: Insights and Roles in Heterocyclic Chemistry Volume 2: Hydantoins Thiohydantoins and 2 5-Diketopiperazines | Science Client Lines